Biggest ever map of human Alzheimer’s brain published

Alzheimer’s Research UK | February 2019| Biggest ever map of human Alzheimer’s brain published

A study of the differences between healthy brains and those with Alzheimer’s Disease has produced largest dataset of its type ever.

The team included researchers from the Universities of Manchester, Bristol, Liverpool and Auckland. The dataset is now freely available online for any scientist to use.

The research team also show that one region of the brain previously thought to be unaffected by the disease, the cerebellum, displayed a series of changes which they think might protect it from damage caused by Alzheimer’s.

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The development is an important advance for scientists researching Alzheimer’s. Their analysis, mapped the relative levels of over 5,825 distinct proteins across six regions of the brain, generated a massive 24,024 data points.

The brain regions in the study included the more heavily affected Hippocampus, Entorhinal cortex, Cingulate gyrus and the less affected Motor Cortex, Sensory Cortex, and Cerebellum.

Full details from Alzheimer’s Research UK

See also: University of Manchester Biggest ever map of human Alzheimer’s brain published

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