Long-term risk of dementia among people with traumatic brain injury

Brain injuries increase dementia risk, study finds | The Lancet Psychiatry | BBC News

A study published in The Lancet Psychiatry suggests that people who suffer brain injuries are at increased risk of dementia later in life. An analysis of 2.8 million people found those who had one or more traumatic brain injuries were 24% more likely to get dementia than those who had not. The risk was greatest in people who had the injuries in their 20s, who were 63% more likely to get the condition at some point in their life.

Previous research has suggested a link between brain injuries – leading causes of which include falls, motor vehicle accidents, and assaults – and subsequent dementia, but evidence has been mixed.

This new study, which followed people in Denmark over a 36-year period, found those who had experienced even one mild Traumatic Brain Injury (concussion) were 17% more likely to get dementia, with the risk increasing with the number of TBIs and the severity of injury.

Sustaining the injury at a younger age appeared to further increase the risk of getting the condition, the research found.  Those who suffered a TBI in their 30s were 37% more likely to develop dementia later in life, while those who had the injury in their 50s were only 2% more likely to get the condition.

Full story via BBC News

Fann, Jesse R et al. | Long-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study | The Lancet Psychiatry | Published: 10 April 2018

See also: Does traumatic brain injury hold the key to the Alzheimer’s disease puzzle? | Azheimers and Dementia | April 2018 | Volume 14, Issue 4 |  pages 431–443


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