New research shows where in the brain the earliest signs of Alzheimer’s occur

Researchers have convincingly shown where in the brain the earliest signs of Alzheimer’s occur.  Nature Communications | Story via ScienceDaily

In Alzheimer’s, the initial changes in the brain occur through retention of the protein, ?-amyloid (beta-amyloid). The process begins 10-20 years before the first symptoms become noticeable in the patient.

In Nature Communications, a research team has presented results showing where in the brain the initial accumulation of ?-amyloid occurs.  It is hoped that the discovery could potentially become significant to future Alzheimer’s research while contributing to improved diagnostics.

Full story at ScienceDaily

Link to the research: Palmqvist, S et al. Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity. Nature Communications, 2017; 8 (1)

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