Deep and Frequent Phenotyping Study: Dementia Early Detection and Biomarkers Research Programme (MRC / NIHR)

Dementia and Elderly Care News


The Deep and Frequent Phenotyping Study will explore improvements in biomarker research and the development of tests to detect Alzheimer’s Disease early on. This research programme will be funded by the National Institute of Health Research (NIHR) and the Medical Research Council (MRC).

“The Deep and Frequent Phenotyping study will recruit 250 volunteers from existing study cohorts led by the Dementias Platform UK”.

The ultimate aim is to improve the success rate of clinical trials for treatments in Alzheimer’s Disease – many of which have failed – probably due to the interventions under investigation starting a too late a phase in disease progression, after irreparable damage has taken place.

The biomarkers and tests under investigation will include:

  • Monitoring alterations in movement and walking (“gait”) assessments, using wearable devices.
  • Ophthalmological assessments of the retina.
  • Magnetic Resonance Imaging (MRI) brain scans.
  • Magnetoencephalography (MEG) to measure the magnetic fields produced by…

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